Sunday, November 02, 2008

Low Progesterone, Clomid as treatment

Reasons ,Symptoms ,Results of Low Progesterone

Progesterone is a steroid hormone made by the ovary at ovulation and in low amounts by the adrenal glands. Progesterone is manufactured in the body from the steroid hormone pregnenolone, and is a precursor to most of the other steroid hormones, including cortisol, androstenedione, the estrogens and testosterone. When there is a low progesterone level, it needs to be replaced. The most important role of progesterone is to balance or oppose the effects of estrogen.

When progesterone levels are low the following symptoms may occur:

* Depression * Decreased libido * Fibrocystic breasts * Food and sugar cravings * Uterine fibroids * Irregular or excessive uterine bleeding * Endometriosis * PMS * Infertility * Weight gain * Increased blood clotting * Thyroid dysfunction

Three symptoms of low progesterone include early disintegration of the corpus luteum, poor follicle production, and the failure of the uterine lining to respond to normal levels of progesterone, which may cause a miscarriage. One way to determine if low progesterone is the problem is by charting your basal body temperature. If the temperature drops early after ovulation, usually before the tenth day, there might be a problem with progesterone levels. Another way to determine if there is enough progesterone to sustain the pregnancy is with an endometrial biopsy. This is a test where a small section of uterine tissue is removed during the second half of a woman’s cycle to determine if it is developing correctly.

Why Clomid is taken ???

Clomid is actually quite a potent and somewhat complicated medication. It is capable of reacting with all of the tissues in the body that have estrogen receptors. These tissues include hypothalamus, pituitary, ovary, endometrium, vagina, and cervix. Clomid influences the way that the four hormones required for ovulation, GnRH, FSH, LH and estradiol, relate and interrelate. While we do not completely understand the mechanisms by which this drug works, in essence it appears that Clomid fools the body into believing that the estrogen level is low. This altered feedback information causes the hypothalamus (an area of the brain) to make and release more gonadotropin releasing hormone (GnRH) which in turn causes the pituitary to make and release more FSH and LH. More follicle stimulating hormone and more luteinizing hormone should result in the release of one or more mature eggs - ovulation.

Clomid Intake increase/Decrease & when ,what days?

When used for ovulation induction, Clomid is taken orally for approximately five days early in the menstrual cycle. Depending upon your clinic protocol this may start as early as day 3 or as late as day 5. It is important to remember that the first day of the menstrual cycle is the first day of normal bleeding, not spotting. Most women begin with an initial dose of one tablet (50 mg.) per day. This dose may be increased by your physician in subsequent cycles if pregnancy does not occur. Once ovulating, most pregnancies occur in the first 6 cycles of treatment. Clomid is said to be able to induce ovulation in as much as 85% of the women who use it, though only half of those will actually become pregnant. Most authorities agree that continuing for more than 6 ovulatory cycles in not likely to increase the chances of success.

At many clinics a pelvic examination or ultrasound is done each cycle shortly before starting on CC in order to determine if there are any ovarian or uterine abnormalities. Approximately 5% of women using Clomid will develop an ovarian cyst at some time during their treatment period. These cysts are benign and will usually resolve spontaneously without any treatment, but may cause discomfort. If you are using Clomid and do not have a menstrual period by cycle day 35, you may have failed to ovulate or you may be pregnant! In either event you need to schedule a visit to your doctor to ascertain what is happening. If you are not pregnant, your doctor may prescribe other medications to help bring on your period. Extended luteal phases (late periods, long cycles) are not uncommon on Clomid.

What are the side effects of Clomiphene?

Twin pregnancies may occur in as many as 5% of the women who use Clomid. Triplet pregnancies are far more rare. Other reported adverse effects include ovarian enlargement 13.6%,Vasomotor Flushes 10.4%, abdominal or pelvic discomfort, distention or bloating 5.5%, nausea and vomiting 2.2%, breast discomfort 2.1%, visual symptoms (blurred vision, lights, floaters, waves, unspecified visual complaints, photophobia, diplopia, scotoma, etc.) 1.5%, headache 1.3% and abnormal uterine bleeding (intermenstrual spotting, menorrhagia)

Did your OB&GYN discuss all these ,Side effects of Clomid,Increase or decrease of clomid and explain how ovulation takes place ,if no please refer following URL :

http://www.oasisserene.com/hormones… http://infertility.about.com/cs/clo… http://www.fwhc.org/health/moon.htm… http://www.conceivingconcepts.com/l… http://www.conceivingconcepts.com/c…

Personal Recommendation Instead of KY Jelly or Astroglide or Replens try using Pre-seed lubricant next time during your intercourse,cause most of time's Sperms cant be motile in the above lub's and if they are motile upto 70% than they can't sustain life of 20-24 hours long ,so better use Pre-seed,it costs something around 170-180$ & can be used atleast 6-10 times,but it work wonders.

Am I /Will I be Pregnant : Well dear its really too early to say these cause mostly after using Clomid the success rate for Conception is around 25-40% not more.Better see the Cervical Mucus change,Measure your Leutal phase (14 days by default) and measure your basal temp ,if you get mid ovulation pain than yes you are pregnant and if you have leautal problem we recommend at times for few patients to watch leautal phases of Moon that also makes difference at times.Though its just natural remedy.

Rate = 4 (Rated by 11 Council Members)

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